No More Monkeying Around: Primate Malaria Model Systems are Key to Understanding Plasmodium vivax Liver-Stage Biology, Hypnozoites, and Relapses
Plasmodium vivax is a human malaria parasite responsible for significant morbidity worldwide and potentially death.This parasite possesses formidable liver-stage biology that involves the formation of dormant parasites known as hypnozoites.Hypnozoites are capable of activating weeks, months, or years after a primary blood-stage infection causing re