NO MORE MONKEYING AROUND: PRIMATE MALARIA MODEL SYSTEMS ARE KEY TO UNDERSTANDING PLASMODIUM VIVAX LIVER-STAGE BIOLOGY, HYPNOZOITES, AND RELAPSES

No More Monkeying Around: Primate Malaria Model Systems are Key to Understanding Plasmodium vivax Liver-Stage Biology, Hypnozoites, and Relapses

Plasmodium vivax is a human malaria parasite responsible for significant morbidity worldwide and potentially death.This parasite possesses formidable liver-stage biology that involves the formation of dormant parasites known as hypnozoites.Hypnozoites are capable of activating weeks, months, or years after a primary blood-stage infection causing re

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Formulation and in vitro evaluation of Eudragit S-100 coated naproxen matrix tablets for colon-targeted drug delivery system

The purpose of the present investigation was to prepare matrix tablets of naproxen using a hydrophobic polymer, i.e., Eudragit RLPO, RSPO, and combination of both, by wet granulation method.The tablets were further coated with different concentrations of Eudragit S-100, a pH-sensitive polymer, by dip immerse method.In vitro drug release studies of

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